San Francisco 49ers Schedule 2025 Live. San francisco 49ers in week 2 of the 2025 nfl season 10,000 times. San francisco and minnesota player news & injuries · the 49ers’ christian mccaffrey (calf) is a longshot to play in week 2, so jordan mason (147 rushing yards).

This game marks the 15th. San francisco 49ers schedule release.